bet365 online sports betting app title: Revealing high-quality genomes of poppy speciesBIALeap-forward bet365 online sports betting app metabolic pathways
bet365 online sports betting app Announcement Person: bet365 online sports betting app
Reporting location: Tencent Conference634-404-288
bet365 online sports betting app time:2022Year10month23Sunday morning11:00
Master hold Person: Guo Fei
bet365 online sports betting app Introduction:
For millions of years, plants evolve plenty of structurally diverse secondary metabolites (SM) to support their sessile lifestyles through continuous biochemical bet365 online sports betting app innovation. While new genes commonly drive the evolution of plant SM bet365 online sports betting app, how a full biosynthetic bet365 online sports betting app evolves remains poorly understood. The evolution of bet365 online sports betting app involves recruiting new genes along the reaction cascade forwardly, backwardly, or in a patchwork manner. With three chromosome-scale Papaver genome assemblies, we here reveal whole genome duplications (WGDs) apparently accelerate chromosomal rearrangements with a nonrandom distribution towards SM optimization. A burst of structural variants involving fusions, translocations and duplications within 7.7 million years have assembled nine genes into the benzylisoquinoline alkaloids gene cluster, following a punctuated patchwork model. Biosynthetic gene copies and their total expression matter to morphinan production. Our results demonstrate how new genes have been recruited from a WGD-induced repertoire of unregulated enzymes with promiscuous reactivities to innovate efficient metabolic pathways with spatiotemporal constraint.
Speaker profile:Yang Xiaofei，Doctor，Currently an associate professor at the School of Computer Science and Technology, Xi'an Jiaotong bet365 online sports betting app，Doctoral Supervisor，Member of the Bioinformatics Committee of the Computer Society，Member of the Computing and Bioinformatics Committee of the Chinese Society for Bioengineering。2019Shaanxi Province Outstanding Doctoral Thesis。Graduated with a PhD in computer application technology from Xi'an bet365 online sports betting app of Electronic Science and Technology。2018Year10month-2019Year10Worked as a visiting scholar at the Jackson Laboratory in the United States。Mainly engaged in multi-omics data analysis and algorithm development，Includes genome assembly and annotation、Development of structural variation detection algorithm, etc.，Host the National Natural Science Foundation of China project，Youth Project、Participate in the key R&D programs of the Ministry of Science and Technology, etc.。Published bet365 online sports betting app papers in total30Remaining articles, includingbet365 online sports betting app, Nature Communications, Nature methods, bet365 online sports betting app Biology, Briefings in Bioinformatics and other journals, cumulative citations of published papers1100Remaining times, highest single citation209times, there are papers with more than 100 citations5Articles,h-indexfor15.
