bet365 sports betting title: Multi-domain protein structure and function prediction
bet365 sports betting Announcement Person: Zhou Xiaogen
Reporting location: Tencent Conference312-421-117
bet365 sports betting time:2022Year10month27Sunday afternoon15:00
Master hold Person: Guo Fei
bet365 sports betting Introduction: Protein structure prediction is the basis for elucidating functional mechanisms and revealing the biological nature of living organisms，is to accelerate disease research and promote innovative drug development、Core technology for vaccine design and precise diagnosis。AIbet365 sports betting prediction programAlphaFold2A major breakthrough in accurately predicting bet365 sports betting tertiary structure based on amino acid sequence。AlphaFold2Although the accuracy is higher，However, the accuracy of full-length structure modeling of multi-domain proteins still needs to be further improved，And the functions of domain conclusion and collaboration are crucial。This bet365 sports betting introduces the reporter’s work on multi-domain protein structure assembly and function prediction，Includes multi-domain protein assembly methods based on similar templates、Progressive assembly method of multi-domain protein structures assisted by cryo-EM density map、Fully automated multi-domain protein structure and function deep learning prediction platform。
Speaker profile:Zhou Xiaogen，Doctor，Distinguished Professor of Canal Young Scholars at Zhejiang bet365 sports betting of Technology。2018Graduated from Zhejiang bet365 sports betting of Technology,2018To2021Worked as a postdoctoral researcher in Zhang Yang’s laboratory at the bet365 sports betting of Michigan。Research direction is structural bioinformatics、Computational intelligence and deep learning。Currently hosting the National Natural Science Youth Foundation project1item; the first author isPNAS，Nature Computational Science、Nature Protocols、Nucleic Acids Research、Bioinformatics、IEEEPublished papers in journals such as Transactions14; won the Zhejiang Province Outstanding Doctoral Thesis Award; developedDEMO、DEMO-EMandI-TASSER-MTDbet365 sports betting modeling and function prediction server，Already served from60Users from multiple countries and regions.
