bet365 casino live blackjack title:Joint Learning of Multiple Gene Networks based on Gaussian Graphical Models
bet365 casino live blackjack Announcement Person:Ouyang Le
Reporting location: Tencent Conference750-549-502
bet365 casino live blackjack time:2022Year10month28Sunday afternoon14:30
Master hold Person: Guo Fei
bet365 casino live blackjack Introduction:
Gaussian Graphical models have been widely used to learn the conditional dependence structures among random variables. In many controlled experiments, such as the studies of disease or drug effectiveness, learning the structural changes of gene networks under different conditions is of great importance. However, most existing graphical models are developed for estimating a single graph and based on a tacit assumption that the differences between networks are driven by individual edges, and there is no missing relevant variables, which wastes the common information provided by multiple heterogeneous data sets, and may fail in identifying driver genes that lead to the changes of networks, and underestimates the influence of latent/unobserved relevant variables. In this talk, to address the above problems, I will introduce several Gaussian graphical model-based network inference methods. Extensive simulation experiments demonstrate that these models outperform other state-of-the-art methods in estimating the structural changes of graphical models. Moreover, a series of experiments on several real-world data sets have been performed and experiment results consistently show that our proposed methods are effective in identifying gene networks under different conditions.
Speaker profile:Ouyang Le, associate professor and doctoral supervisor at Shenzhen bet365 casino live blackjack. At2015Year6Received a Doctorate of Science from Sun Yat-sen bet365 casino live blackjack;2013Year-2014Year，Going to the Department of Computer Science, Nanyang Technological bet365 casino live blackjack, Singapore for an exchange visit。2015Year-2016Engaged in postdoctoral research in the Department of Electronic Engineering, City bet365 casino live blackjack of Hong Kong。Mainly engaged in data mining、Scientific research and teaching work in the fields of machine learning and bioinformatics。Winner of the top young talents of Guangdong Province’s Pearl River Talent Plan and Shenzhen bet365 casino live blackjack’s Liyuan Outstanding Youth。Presided over a number of national, provincial and ministerial level scientific research projects，alreadyIEEE TCYB、Bioinformatics、Briefings in Bioinformatics、Pattern RecognitionPublished in other international journalsSCIPaper50More articles. serveBioinformatics、PLoS Computational Biology、Briefings in Bioinformatics、IEEE JBHI、Communication BiologyReviewer of other important publications,AAAI、IJCAI、ICMLMember of the program committee of other international bet365 casino live blackjack conferences.
